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421/422 Projects

Positions for the 2019-20 Academic Year are now complete.  This page will be updated in December for those in third year beginning September 2020.

SSP Project/Supervisor Selection:

Step 1: You will find all projects listed on our website beginning December 20, 2019. You will have an opportunity to go through them over the holidays to see where your interest is. 

Step 2: Once you return in January you are encouraged to meet with potential supervisors if you have questions about the lab and research project.  Supervisors will not be able to guarantee you will be selected to their lab.

Step 3: You can go to this document: https://docs.google.com/forms/d/1VxPqndTe_7XAFVAHx7FbVSQaFcaIeoBYopjWhAgGVEg to rank your top three selections. The document will open on January 3, 2020 and close at 4pm on January 31, 2020. We will endeavor to do our best to give you one of your choices.  Please only submit your choices once.

Step 4: In the case where more than one person have listed the same supervisor for 1st choices, the supervisor will be given the opportunity to choose.  Keep in mind that there is no guarantees or promises given to students in advance of our decision.   

Step 4: You will know by February 14, 2020 who your supervisor will be and which project you will be working on.

Step 5: Once final marks in May have been received we will ensure that everyone meets the requirements to be in BCHM 421 and BCHM 422. PREREQUISITE: Level 4 and (registration in a BCHM Specialization Plan) and (a GPA of 2.9 in BCHM 313/3.0, BCHM 315/3.0, BCHM 316/3.0, BCHM 317/6.0, BCHM 218/3.0). Final approval will be complete by May 10, 2019.

 

Participating Faculty 2020-2021:

SUPERVISOR      PROJECT TITLE

Craig, Andrew        A novel melanoma subtype defined by chromosome 19 miRNA cluster expression

Davies, Peter #1     Discovery of new ligand-binding domains in bacterial adhesins

Davies, Peter #2     Structure-function relationships in ice nucleation proteins

Jia, Zongchao #1     Structure-guided inhibition of polyphosphate kinases in P. aeruginosa as a novel antivirulence approach

Jia, Zongchao #2     Polyphosphate biosynthesis as a virulence factor determinant in multi-drug resistant bacterial pathogens

Ormiston, Mark       Examining the contribution of Activin Type II Receptors to the pathological endothelial cell phenotype in pulmonary arterial hypertension

Plaxton, William      Molecular, regulatory, and functional properties of key enzymes of plant carbohydrate and phosphate metabolism

Smith, Steven         Engineering designer enzyme complexes for directed production of biomass-based high-value chemicals

Snedden, Wayne     Investigating calcium signal transduction in plants

 

Participating Faculty 2019-2020:

SUPERVISOR   PROJECT TITLE

Abraham, Sheela #1   Extracellular Vesicle Biogenesis in Chronic Myeloid Leukaemia

Abraham, Sheela #2   How extracellular vesicles effect stem cell function in Chronic Myeloid Leukaemia

Allingham, John   Investigating the roles of kinesin motors in genome plasticity of Candida albicans

Capicciotti, Chantelle   Investigating Glycan-Protein Interactions in Cells with Photo-Crosslinking Probes

Chan, Edmond #1 Regulation of mitochondria fusion machinery by nutrient stress

Chan, Edmond #2 Role for mitochondria dynamics in cancer cell growth

Craig, Andrew  Defining targets of tumour suppressor microRNAs in malignant melanoma

Craig, Andrew & Allingham, John   Developing novel actin-targeting antibody drug conjugates for metastatic cancers

Davies, Peter #1   Discovery of new ligand-binding domains in bacterial adhesins

Davies, Peter #2   Discovery and characterization of new antifreeze proteins

Davies, Peter #3   Structure-function relationships in ice nucleation proteins

Davies, Peter #4   Structure, function and inhibition of the calcium-activated calpain-3 protease

Ghasemlou, Nader #1   Profiling circadian rhythms in sensory neuron

Ghasemlou, Nader #2   Dissecting the inflammatory component of spinal cord injury pain

Jia, Zongchao #1   Structure-guided inhibition of polyphosphate kinase in P. aeruginosa as a novel antivirulence approach

Jia, Zongchao #2   Polyphosphate biosynthesis as a virulence factor determinant in multi-drug resistant bacterial pathogens

Mueller, Christopher #1   A blood test for directing Immunotherapy in Lung Cancer

Mueller, Christopher #2   A blood test for Prostate Cancer, replacing PSA

Mueller, Christopher #3   A blood test for Breast Cancer, replacing mammography

Ormiston, Mark   Examining the impact of non-coding RNAs on the phenotype and function of pulmonary endothelial cells following silencing of the bone morphogenetic protein type II receptor

Plaxton, William  Molecular, regulatory, and functional properties of key enzymes of plant carbohydrate and phosphate metabolism

Ross, Avena      Genome Guided Discovery of Marine Natural Products

Smith, Steven   Engineering designer enzyme complexes for directed production of biomass-based high-value chemicals

Snedden, Wayne   Investigating calcium signal transduction in plants

Wu, Gang & Smith, Steven  Synthesis of 17O-labeled amino acids and their incorporation into proteins

Zechel, David #1    Biosynthesis of a Fluorinated Natural Product in Streptomyces calvus

Zechel, David #2   The mechanisms and substrate specificities of the phosphonate degrading enzymes PhnY and PhnZ